Abstract

The use of targeted toxins in research applications has recently grown considerably. The ability to remove a few specific cells, even when surrounded by different populations, has given scientists a powerful tool for the understanding of systems biology. The use of targeted toxins in research is rich and varied; here we limit ourselves to describe some of those exciting results that researchers have made in the neurosciences.

Keywords: immunotoxin, ligand-toxin, peptide-toxin, saporin, retrograde transport, behavior, molecular surgery, molecular neurosurgery