Author(s): Marlon Cowart, Robert Altenbach, Lawrence Black, Ramin Faghih, Chen Zhao and Arthur A. Hancock
Page: [979 - 992] Pages: 14
* (Excluding Mailing and Handling)
The H3 receptor is prominently expressed in neuronal tissues, and H3 antagonists have been proposed as drugs with benefits in disorders of cognition, attention, pain, allergic rhinitis, and obesity. The structure-activity relationships (SAR) of various classes of non-imidazole H3 antagonists are reviewed, along with highlights of functional efficacy in tissue-based and animal disease models.
Keywords: non-nimidazole, histamine, h3, review, antagonist, inverse agonist
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