Author(s): I. J.P. De Esch and K. J. Belzar
Page: [955 - 963] Pages: 9
* (Excluding Mailing and Handling)
The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimesconflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date.
Keywords: histamine, h3, gpcr, agonist, isoform, activity, efficacy, affinity
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