Mini-Reviews in Medicinal Chemistry

Author(s): Dj. Miljkovic, M. Markovic and V. Trajkovic

DOI: 10.2174/1389557043403585

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Inducible Nitric Oxide Synthase Inhibition by Mycophenolic Acid

Page: [741 - 746] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

The focus of this review is the influence of an immunosuppressive xenobiotic drug mycophenolic acid on the induction of nitric oxide production in various cell types. The potential therapeutic significance of the cell-specific fine-tuning of nitric oxide release by mycophenolic acid, as well as the mechanisms behind the drug action are discussed.

Keywords: mycophenolic acid, mycophenolate mofetil, nitric oxide, inos