Letters in Organic Chemistry

Author(s): Martin G. Kociolek, Nicholas G. Straub and Elizabeth J. Marton

DOI: 10.2174/1570178053765302

DownloadDownload PDF Flyer Cite As
Synthesis of β-Ketonitriles from 3-Bromoisoxazoles

Page: [280 - 282] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

A series of substituted 3-bromoisoxazoles were ring opened with either molybdenum hexacarbonyl or iron (II)chloride tetrahydrate to give β -ketonitriles in good yields.

Keywords: isoxazole, ketonitrile, molybdenum hexacarbonyl, ferrous chloride, reductive ring opening