Abstract

This paper reviews the latest developments in the synthesis of swainsonine and its analogues since the first review in this area by Nemr which covered the literature up to 1999 (Nemr, A. E. Tetrahedron 2000, 56, 8579- 8629).

Keywords: swainsonine, ring-closing metathesis, ruthenium catalysed rearrangement, epoxide, dihydroxylation, indolizine, pyrrolidine, meso compounds, asymmetric desymmetrization, enzyme kinetic resolution