Letters in Organic Chemistry

Author(s): Xiao-yu Wu, Xiang-guo Li and Gang Zhao

DOI: 10.2174/1570178053400054

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Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone

Page: [65 - 67] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

The copper-catalysed asymmetric conjugate addition of diphenylzinc to 2-cyclohexenone has been carried out with good results. An enantiometric excess of up to 91% was obtained using 5 mol% CuI and 5 mol% phosphine ligand derived from L-proline.

Keywords: copper-catalyzed, conjugate-addition, diphenylzinc, phosphine, ligand