Abstract

The various synthetic methodologies for constructing the β-mannosidic bonds have been reviewed. Different strategies are covered such as inter and intramolecular glycosidation methods as well as epimerization of β-glucosides, reductive cleavage of anomeric orthoesters, radical anomeric inversion, enzymatic synthesis and mannosides from non-carbohydrate.

Keywords: glycosyl acceptors, mannosyl donor, aglycon delivery, epimerization, b-mannopyranosides, stereoselective mannosidation, 1,2-cis-mannosides, benzylsulfonyl