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Letters in Organic Chemistry

Author(s): V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna and A. Mehta

DOI: 10.2174/157017805774296876

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A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones

Page: [637 - 639] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.

Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation