Letters in Organic Chemistry

Author(s): W.- W. Yang, L.- F. Cun, Y.- G. Zhi, A.- Q. Mi, Y.- Z. Jiang and L.- Z. Gong

DOI: 10.2174/157017805774296939

The Chiral N-Monosubstituted 1,2-diphenyl-2-aminoethanols Promoted Enantioselective Diethylzinc Addition to In Situ Formed Imines

Page: [605 - 607] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

The use of easily accessible N-monosubstituted 1,2-diphenyl-2-aminoethanols as ligands to promote the asymmetric addition of diethylzinc to alkyl- and arylimines generated in situ from the precursors provided optically active N-diphenylphosphinylamines with enantioselectivities of up to 96% ee.

Keywords: asymmetric catalysis, amino alcohols, diethylzinc addition, imines