Author(s): K. M. Khan, S. Ahmed, Z. A. Khan, M. Rani, S. Perveen, M. I. Choudhary and Atta-ur-Rahman
Page: [532 - 534] Pages: 3
* (Excluding Mailing and Handling)
A microwave-assisted, environment friendly, high yielding, time saving synthesis of medicinally important 3-substituted isocoumarins was carried out in a single step by the direct condensation of homophthalic acid with aryol and acyl chlorides under the solvent-free conditions without any solid support. The synthesized isocoumarins were structurally characterized by microanalysis, 1H-NMR, EI, IR and UV.
Keywords: microwave-irradiation, homophthalic acid, substituted isocoumarins
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