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Mini-Reviews in Medicinal Chemistry

Author(s): A. Gasco, R. Fruttero and B. Rolando

DOI: 10.2174/1389557053402684

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Focus on Recent Approaches for the Development of New NO-Donors

Page: [217 - 229] Pages: 13

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Abstract

Recent research developments in the field of NO-donor compounds have concerned conjugation of NO-donor moieties with antioxidant groups, NO-donor targeting, design of NO-donor hybrid drugs and of NOdelivery systems. These new approaches are illustrated and discussed through selected examples.

Keywords: nitric oxide, no-donors, no-donor antioxidants, no-donor targeting, drug/no-donor hybrids, no-delivery systems