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Letters in Organic Chemistry

Author(s): Shivaji S. Pawar, Murlidhar S. Shingare and Shivaji N. Thore

DOI: 10.2174/157017807782006371

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A Novel Approach for Ligand Promoted Palladium (II)-Catalyzed Suzuki Coupling of Aryl Iodides and Bromides with Arylboronic Acid in Aqueous Media

Page: [486 - 490] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

A highly efficient, environmental friendly, palladium (II) catalyzed ligand promoted Suzuki reaction in aqueous phase was developed in short reaction time (4 - 5 h) at room temperature. The key for such a successful catalytic system was the use of suitable amount of co-solvent in the aqueous phase and reuse of palladium catalyst.

Keywords: Aqueous media, suzuki-coupling reaction, PdCl2[P(Ph)3]2catalyzed, aryl iodides and bromides, boronic acid, reuse of catalyst