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Letters in Organic Chemistry

Author(s): Janaina Versiani dos Anjos, Denis Sinou, Sebastiao Jose de Melo and Rajendra Mohan Srivastava

DOI: 10.2174/157017807781467579

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Synthesis of Ethyl 4-O-[4-(1,2,4-Oxadiazol-5-yl)phenyl]-α-D-mannopyranosides

Page: [393 - 397] Pages: 5

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Abstract

The palladium-catalyzed reaction of 5-(4-hydroxyphenyl)-1,2,4-oxadiazoles with ethyl α-O-Δ2-glucopyranoside afforded ethyl 4-O-[4-(1,2,4-oxadiazol-5-yl)phenyl]-2,3-dideoxy-α-D-erythro-hex-2-enopyranosides. Bishydroxylation of the latter compounds gave the corresponding ethyl 4-O-[4-(1,2,4-oxadiazol-5-yl)phenyl]-α-Dmannopyranosides.

Keywords: 1,2,4-Oxadiazole, palladium catalyst, ethyl α-O-Δ2-glycoside, ethyl mannopyranoside