Abstract

Flavonoids are ubiquitously in plants which have been shown to possess a variety of biological activities at nontoxic concentrations in organisms. Compelling data indicate that flavonoids have important effects on cancer chemoprevention and chemotherapy, till now, much research has been done about their potential anticancer effect. In this review the discovery and development of flavonoids as potential anticancer agents in recent years have been summarized.

Keywords: Flavonoids, anticancer agents, discovery, development, clinical trial, mechanism, cytotoxicity, SAR