Generic placeholder image

Letters in Organic Chemistry

Author(s): Naminita Gogoi, Jagat C. Borah, Joshodeep Boruwa and Nabin C. Barua

DOI: 10.2174/157017807781024192

DownloadDownload PDF Flyer Cite As
Lipase Catalysed Kinetic Resolution of 2-Nitroalcohol: Total Synthesis of Taxol Side Chain and (-)-Bestatin

Page: [234 - 235] Pages: 2

  • * (Excluding Mailing and Handling)

Explore Articles
About Journal
For Authors
For Editors
For Reviewers

Abstract

2-Nitroalcohols were efficiently resolved by Lipase catalysed transesterification process. This protocol was successfully applied to the synthesis of taxol side chain and (-)-bestatin in overall yields of 40% and 20% respectively.

Keywords: Taxol Side Chain, (-)-Bestatin, lipase catalysed kinetic resolution