Abstract

New prostaglandins analogues, containing heteroatoms in the cyclopentane ring were synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from L-cysteine ethyl ester hydrochloride. The addition of the alkyl groups at C-15 position was also performed.

Keywords: Heterocyclic prostaglandins, azaprostaglandins, thiaprostaglandins