Protein & Peptide Letters

Author(s): Ludmila S. Koroleva, Inna Yu. Serpokrylova, Valentin V. Vlassov and Vladimir N. Silnikov

DOI: 10.2174/092986607779816177

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Design and Synthesis of Metal-Free Artificial Ribonucleases

Page: [151 - 163] Pages: 13

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Abstract

The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.

Keywords: Artificial ribonucleases, RNases mimics, oligonucleotide conjugates