Author(s): I. A. Velter, M. Politi, C. Podlipnik and F. Nicotra
Page: [159 - 170] Pages: 12
* (Excluding Mailing and Handling)
Cholera Toxin (CT) recognizes the cell membrane through specific interactions with ganglioside GM1. Recent structural elucidation of the CT/GM1 complex has allowed the rational design of artificial receptors for the toxin, which could function as anti-cholera drugs. The efforts towards the rational design of Cholera Toxin inhibitors will be presented.
Keywords: Cholera toxin, ganglioside GM1, catechins, galactose, multivalency
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