Mini-Reviews in Medicinal Chemistry

Author(s): S. Kralisch, M. Bluher, R. Paschke, M. Stumvoll and M. Fasshauer

DOI: 10.2174/138955707779317821

Adipokines and Adipocyte Targets in the Future Management of Obesity and the Metabolic Syndrome

Page: [39 - 45] Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulinsensitizers/ insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.

Keywords: Adipokine, diabetes mellitus, insulin resistance, obesity