Cannabinoid Receptor Antagonists and the Metabolic Syndrome: Novel Promising Therapeutical Approaches

C.      Cervino; R.      Pasquali; U.      Pagotto

Mini-Reviews in Medicinal Chemistry

Author(s): C. Cervino, R. Pasquali and U. Pagotto

DOI: 10.2174/138955707779317812

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Cannabinoid Receptor Antagonists and the Metabolic Syndrome: Novel Promising Therapeutical Approaches

Page: [21 - 30] Pages: 10

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Abstract

Recent findings in animals and in humans have shown that cannabinoid type 1 receptor antagonists are suitable to become the most promising validated class of drugs to tackle obesity and related disorders. This mini-review will provide a concise and updated revision of the state of art on this topic.

Keywords: Endocannabinoid, cannabinoid type 1 receptor, cannabinoid type 1 receptor antagonist, rimonabant, metabolic syndrome

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