Abstract

A series of multicomponent reactions has been carried out using HClO4-SiO2 as a versatile catalyst. A series of medicinally important heterocyclic core structures have been prepared under solvent-free reaction conditions. In all cases, the reaction conditions were very simple and high yielding.

Keywords: Multicomponent reaction, Pechmann reaction, coumarin, Biginelli reaction, hetero-Diels-Alder, Hantzsch reaction, pyranoquinoline