Mini-Reviews in Medicinal Chemistry

Author(s): G. Batoni, G. Maisetta, S. Esin and M. Campa

DOI: 10.2174/138955706778560193

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Human Beta-Defensin-3: A Promising Antimicrobial Peptide

Page: [1063 - 1073] Pages: 11

  • * (Excluding Mailing and Handling)

Abstract

The field of naturally occurring antimicrobial peptides is a research area rapidly expanding due to the high potential of such molecules as new antimicrobial drugs. In this regard, the human beta-defensin-3 is particularly attractive because of its strong antibacterial activity, relative salt-insensitiveness and low toxicity for host cells.

Keywords: Antimicrobial peptides, human beta-defensin-3, drug resistant microorganisms, new antimicrobial drugs, peptide structure