Abstract

Catalytic RNAs, known as ribozymes, act as true enzymes and are implicated in important biological processes, such as protein synthesis, mRNA splicing, transcriptional regulation and retroviral replication. Ribozymes are capable of serving as a new molecular target for a variety of drugs and as a reliable screening system for their biological activity.

Keywords: Ribozymes, RNase P, ribosome, drug target, aminoglycosides, macrolides, retinoids, calcipotriol