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Letters in Organic Chemistry

Author(s): Maria Caterina Viscomi, Angelo Liguori, Francesca Perri, Adolfo Le Pera, Maria Luisa Di Gioia and Antonella Leggio

DOI: 10.2174/157017806777828466

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Reduction of N-Methoxy-N-Methylamides to the Corresponding Amines with AlCl3/LiAlH4

Page: [468 - 469] Pages: 2

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Abstract

Aromatic and aliphatic Weinreb amides are selectively converted into the corresponding N-methoxy- N-methylamines by treatment with lithium aluminium hydride in the presence of aluminium chloride.

Keywords: lithium aluminium hydride, aluminum chloride, reduction, Weinreb amides, N-Methoxy-N-methylamines