Letters in Organic Chemistry

Author(s): Qingshan Zhang, Yunbo Qu, Wei Chen, Yuan Wang and Qinpei Wu

DOI: 10.2174/157017806776114630

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Mild, Efficient and Highly Selective Hydrolysis of Acetonides with Antimony Trichloride(SUPPORTING INFORMATION)

Page: [271 - 274] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

A mild and efficient procedure for chemoselective and regioselective hydrolysis of acetonide with SbCl3 in the presence of other frequently used hydroxy protecting groups, TBDMS, TBDPS, Bz, Bn, Ac, Ts and Tr, was described. The mechanism was examined and proposed.

Keywords: lewis acid, catalysis, protecting groups, antimony, acetonide, Hydrolysis