A One-Pot Synthesis of D-Ribonucleosides Using Natural Phosphate Doped with KI in HMDS

Hassan   B.   Lazrek; Driss      Ouzebla; Abdellali      Rochdi; Nezha      Redwane; Jean-Jacques      Vasseur

Letters in Organic Chemistry

Author(s): Hassan B. Lazrek, Driss Ouzebla, Abdellali Rochdi, Nezha Redwane and Jean-Jacques Vasseur

DOI: 10.2174/157017806776114531

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A One-Pot Synthesis of D-Ribonucleosides Using Natural Phosphate Doped with KI in HMDS

Page: [313 - 314] Pages: 2

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Abstract

Potassium iodide supported on natural phosphate in HMDS was used as a promotor in the condensation of 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose with trimethylsilylated nucleobases, under mild conditions, to provide several D-ribonucleosides.

Keywords: Natural phosphate, potassium iodide, nucleosides

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