Abstract

An eco-friendly facile synthesis of imidazo[2,1-b]-1,3,4-thiadiazoles is described using ionic liquid, [bmim]PF6 (1-butyl-3-methylimidazolium hexafluorophosphate). The use of recyclable catalyst demonstrates the advantages of significant rate enhancement along with improved yields. The protocol is green and effective for producing the desired target moiety.

Keywords: Thiadiazole, ionic liquid, a-bromoacetophenone, imidazo[2,1-b]-1,3,4-, thiadiazoles