A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.
Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate