Letters in Organic Chemistry

Author(s): Igor Konstantinov, Konstantin Bukhryakov, Yuri Gezentsvey and Mikhail Krasavin

DOI: 10.2174/157017811799304386

Practical Method for Parallel Synthesis of Diversely Substituted 1- henylpiperazines

Page: [628 - 630] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

A simple and practical method to prepare ‘libraries’ of substituted 1-phenylpiperazine building blocks in parallel format has been developed.

Keywords: Bis-alkylation, N-arylpiperazines, nitrogen mustard, parallel synthesis, solvent-free synthesis, SAR-informative, 1-phenylpiperazines, morpholine, iminodiethanol, ethanamine