Letters in Organic Chemistry

Author(s): Wei Chen, Hao Wang, Hua Liu, Yuan Wang and Qinpei Wu

DOI: 10.2174/157017806774964413

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Efficient and Selective Cleavage of Silyl Ethers with Antimony Trichloride

Page: [13 - 15] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

An efficient method for selective cleavage of silyl ethers mediated by SbCl3 in the presence of a number of function groups was described and the primary silyl ethers were hydrolized in the presence of the secondary ethers. The desilyl reaction took much longer time in dry solution than in wet.

Keywords: desilylation, protecting groups, antimony, silyl ethers, catalysis, Hydrolyses