Efficient Microwave and Phosphane-Free Synthesis of Trisubstituted Olefins via Heck Coupling

Guya      Loddo; Ornella      Azzolina; Andrea      Magnani; Mariangela      Urbano; Simona      Collina

Letters in Organic Chemistry

Author(s): Guya Loddo, Ornella Azzolina, Andrea Magnani, Mariangela Urbano and Simona Collina

DOI: 10.2174/157017806774964549

Download PDF Flyer Cite As

Efficient Microwave and Phosphane-Free Synthesis of Trisubstituted Olefins via Heck Coupling

Page: [16 - 20] Pages: 5

* (Excluding Mailing and Handling)

Abstract

We describe an easy and convenient procedure for palladium-catalyzed Heck arylation of disubstituted olefins via microwave irradiation. This method of synthesis produces trisubstituted olefins under phosphane-free conditions and in very short times.

Keywords: microwave irradiation, chemical library, phosphane-free procedure, trisubstituted olefins, Heck reaction

Cite As