Letters in Organic Chemistry

Author(s): Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan-Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter and Javid H. Zaidi

DOI: 10.2174/157017806774964530

Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)

Page: [21 - 24] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Keywords: Neurotensin, partial peptidic mimic, drug design, synthesis