Abstract

Based on the electrostatic interaction between carboxymethylated chitosan (CMCH) and negatively charged CdTe quantum dots, and the selective crosslinking of CMCH using glutaraldehyde(GA), we demonstrated the formation of Fe3O4/SiO2/CMCH/CdTe microspheres. The dense silicate shells of Fe3O4 nano-particles (NPs) protect the luminescence quenching from Fe3O4 NPs, so the composite microspheres have great fluorescence and emulative magnetism. These multifunctional fluorescence/magnetic microspheres lead to robust and water dispersible nanoparticle colloidosomes, and should be of great importance for diagnostics application and specific biological applications.

Keywords: Multifunctional Microspheres, Fe3O4/SiO2/CMCH/CdTe, Fluorescence, Magnetic, Preparation, Characterizations, Biological applications, Diagnostics application, Tracking, Targeting