Abstract

In order to evaluate the anti-hyperglycemic effect of natural compounds via the inhibition of α- glucosidase (AGH), the potential inhibitory effect of anthocyanins, caffeic acid analogs, and caffeoylquinic acid analogs have been reviewed. A new AGH assay system to mimic the membrane-bound AGH at the small intestine was proposed and evaluated.

Keywords: Diabetes, α-glucosidase, maltase inhibition, anti-hyperglycemic effect