Abstract

This review summarizes the recent advances in the field of synthetic fragrance chemistry, with particular emphasis to the following approaches: application of known synthetic protocols to the preparation of new fragrances, lead-structure optimisation of known odorants, and stereoselective synthesis of chiral fragrances.

Keywords: Fragrance, synthesis, odorant, stereoselective synthesis, odour properties, Lewis Super - Acid Catalyzed Cyclizations, Cationic cyclization reactions, Lactoscatone 25, regioisomer, α-pinene oxide, Heck Reaction, sesquiterpene alcohol, Wittig, –, Horner, Emmons reaction, NMR, meta-chloroperbenzoic acid