Current Organic Chemistry

Author(s): Ruimao Hua, Maria Victoria A. Abrenica and Ping Wang

DOI: 10.2174/138527211794519023

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Cycloaddition of Alkynes: Atom-Economic Protocols for Constructing Six-Membered Cycles

Page: [712 - 729] Pages: 18

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Abstract

Recent advances on the synthesis of six-membered carbo- and heterocyclic compounds including functionalized benzenes, 1,3- cyclohexadienes, pyridines, pyridones, pyranones, coumarins and isocoumarins via the cycloaddition reaction of alkynes are reviewed. Special attention is paid to atom-economic controllable chemo- and regioselective reactions, which are currently extremely attractive methodologies in organic synthesis.

Keywords: Alkynes, cycloaddition, carbocycles, heterocycles