Current Drug Targets

Author(s): G. de Crecchio, R. V.P. Chan, G. Manzi and M. R. Romano

DOI: 10.2174/138945011794182782

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Polypoidal Choroidal Vasculopathy: Recent Advances in Therapy

Page: [206 - 211] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

Polypoidal Choroidal Vasculopathy (PCV) is a condition characterized by chronic, multiple, recurrent serous and/or hemorrhagic detachments of the retinal pigment epithelium (RPE) and neurosensory retina. Although it has been described to more often affect Asians and individuals of pigmented races, PCV may also be present in white patients who present with the clinical appearance of age related macular degeneration (AMD). PCV and its treatment are discussed, including the use of combination therapy.

Keywords: Polypoidal choroidal vasculopathy, choroidal neovascularization, age-related macular degeneration, photodynamic therapy, antiVEGF, triamcinolone, combination therapy, retinal pigment epithelium (RPE), neurosensory retina, serosanguinous retinal pigment epithelial (RPE), macula, extrafovea, subfovea, juxtafovea, Optical Coherence Tomography, fundus, Fluorescein Angiography, Indocyanine Green Angiography, hemorrhage, vascular dilations, transpupillary thermotherapy (TTT), Laser Photocoagulation, polypoidal lesion, photothrombosis, Intravitreal Anti-VEGF Therapy, Intravitreal Triamcinolone Acetonide