Abstract

Gliomas are diverse and challenging primary brain tumors that affect an increasing number of adults annually. Although not curable, recent advances in diagnosis and treatment are making a significant impact on length and quality of life. This paper will address the recent advancements, modern management, and current opportunities in glioma diagnosis, imaging and treatment.

Keywords: Glioma, diagnosis, treatment, brain tumor, adult, response assessment, pseudo-progression, O6-methylguanine-DNA methyltransferase, MGMT, Diagnostic Imaging, magnetic resonance spectroscopy, MRS, Peri-Operative Imaging, glial fibrillary acidic protein, GFAP, 18F-labeled fluorodeoxyglucose, FDG-PET, extent of resection, recursive partitioning analysis, RPA, Response Evaluation Criteria in Solid Tumors, RECIST, Response Assessment in Neuro-Oncology, RANO, Chemotherapy, Gliadel