Current Medicinal Chemistry

Author(s): Y. Hou and L. Harinantenaina

DOI: 10.2174/092986710790827834

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New and Bioactive Natural Products Isolated from Madagascar Plants and Marine Organisms

Page: [1191 - 1219] Pages: 29

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Abstract

Madagascar, the worlds fourth biggest island has a unique biodiversity. The interest on the phytochemical investigation of Malagasy plant and marine natural products started from the isolation of the potent anti-cancerous bisindole alkaloids: vinblastine and vincristine. In this paper, work published in the last two decades (1991-2009) on 262 new natural products isolated from Malagasy higher plants, liverworts and marine organisms is reviewed. Several results on the bioassays of the isolated new natural products have been reported.

Keywords: Madagascar, plants, marine organisms, natural products, biodiversity, bioactivities