Abstract

Biologic agents are commonly used in treatment of rheumatoid diseases today. While being very potent in preventing the progression of diseases both clinical and radiological, they have far too many adverse effects as well. Infections, malignity, congestive cardiac failure, injection site reactions, vasculitis, neurological complications and dermatological complications can be mentioned among these adverse effects. In this composition, adverse effects and drug interactions of these biologic agents have been presented in details and with up-to date articles.

Keywords: Biologic agents, adverse effect, drug interactions