Current Organic Chemistry

Author(s): M. Carmen Murcia, Cristina Navarro, Ana Moreno and Aurelio G. Csaky

DOI: 10.2174/138527210790226410

DownloadDownload PDF Flyer Cite As
Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds

Page: [15 - 47] Pages: 33

  • * (Excluding Mailing and Handling)

Abstract

In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.