Current Genomics

Author(s): Jianqiu Zhang, Elias Gonzalez, Travis Hestilow, William Haskins and Yufei Huang

DOI: 10.2174/138920209789177638

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Review of Peak Detection Algorithms in Liquid-Chromatography-Mass Spectrometry

Page: [388 - 401] Pages: 14

  • * (Excluding Mailing and Handling)

Abstract

In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and various peak detection algorithms are described and compared.