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Current Organic Chemistry

Author(s): Shizheng Zhu, Liping Song, Guifang Jin, Baifan Dai and Jian Hao

DOI: 10.2174/138527209788680772

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Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives

Page: [1015 - 1027] Pages: 13

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Abstract

This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.

Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents