Central Nervous System Agents in Medicinal Chemistry

Author(s): Farshad Hassanzadeh Kiabi, Tayebeh Khosravi, Saeed Gharooee Ahangar and Siavash Beiranvand*

DOI: 10.2174/0118715249328823241111101137

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The Importance of Stem Cells in the Treatment of Neuropathic Pain
  • * (Excluding Mailing and Handling)

Abstract

Many disorders, including heart, bone, cancer, liver, and brain disease, have been treated using stem cell therapy as a viable alternative. The somatosensory system is affected by a lesion, which leads to neuropathic pain (NP), and just a relatively tiny fraction of patients now receive effective care from existing pharmacological medications. There have been studies to show the effectiveness of various stem cells in reducing or treating experimental neurological pain, although these studies are uncommon in number. In this narrative review, we will summarize the preclinical and clinical research that has been conducted on the effectiveness of several stem cell types, such as mesenchymal stem cells, bone-derived stem cells, and neural stem cells, in reducing neurological pain in this study.

Keywords: Neurological pain, stem cell therapy, mesenchymal stem cell, neural stem cells, neuropathic pain (NP), brain disease.