Abstract

Background: The application of microfabrication to produce arrays of microscale needles, known as microneedle technology, has greatly improved transdermal drug delivery. This analysis focuses on different types and advances of microneedles to emphasize their tremendous potential in healthcare. Transdermal medication delivery is a common method used in modern medicine to treat a variety of illnesses. By avoiding the hepatic first-pass metabolism, the use of microneedles improves medication penetration via the skin and increases bioavailability.

Method: Using databases like PubMed and Google Scholar, a thorough literature study was carried out to look at the most recent peer-reviewed papers and patents on microneedle technology. Based on factors like size, shape, material, and drug delivery techniques, comparative analysis assessed the safety and effectiveness of several microneedles. Skin physiology was examined to comprehend how permeability enhancers and microneedles affect medication penetration.

Results: Microneedle technology has made significant strides that show it can completely transform medication delivery systems. A large number of patents suggests that research and development are expanding quickly. The market for microneedles is reflecting the increased need for less intrusive medical treatments, highlighting the significance of this method in medical research.

Conclusion: Medical science could be revolutionized by microneedles, especially in the area of drug administration. Researchers and physicians can benefit greatly from this review, which guides the investigation of sophisticated microneedle applications for transdermal treatment of acute or chronic illnesses.

Future Recommendation: Subsequent investigations ought to focus on refining microneedle designs for particular uses, enhancing the biocompatibility of materials, and investigating integration with alternative drug delivery methods. To confirm the safety and effectiveness of microneedle technology in practical medical settings, clinical trials are required.

Keywords: Microneedles, healthcare, advancements, skin, patents, transdermal.