Nanoscience & Nanotechnology-Asia

Author(s): Abul Hasnat, Priyanka Barman, Aakriti Patel, Pratibha Bhowmick and Mithun Bhowmick*

DOI: 10.2174/0122106812333663241106023502

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A Review of Nanocellulose as a Drug Carrier System

Article ID: e22106812333663

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Abstract

Nanocellulose is derived from plant fibers that exhibit extraordinary strength and adaptability at the nanoscale. The nanocellulose is categorized into three different types of namely bacterial cellulose (BC), nanofibrillated cellulose (NFC), and nanocrystalline cellulose (CNC). A few remarkable properties like shape, good surface area, and biological characteristics like biodegradability, biocompatibility, and less toxicity make it unique. Nanocellulose may have usage in antimicrobial applications, drug delivery systems, pharmaceutical coatings, and bioavailability enhancement. The nanocellulose is explored continuously to obtain a thorough knowledge of it in the field of pharmaceuticals. Nanocellulose exhibits remarkable potential as a medication delivery carrier system because of its special properties. Drug distribution to targeted locations inside the human body can be made more effective and selective when nanocellulose is structured and formulated in the form of nanocarrier system. Before nanocellulose is used in pharmaceutical yield it is extracted from plant cell walls there are some extraction methods for each type of nanocellulose. For nanocrystalline cellulose and nano fibrillated cellulose, processes like grinding, homogenization, and acid hydrolysis are employed, while BC is extracted using bacterial culture techniques. Several applications of nanocellulose are now beneficial in terms of pharmaceutical uses as well as pharmacological research, and future study is anticipated to provide more information. The pharmaceutical sector is now researching to test the use of developed nanocellulose in medication delivery systems.

Keywords: Nanocellulose, nanocrystalline cellulose, drug delivery systems, biocompatibility, nanocarrier system, future prospective.