Author(s):
Larry Ellee Nyanti*
,
Nai Chien Huan,
Hema Yamini Ramarmuty,
Rong Lih Ho,
Meryl Grace Lansing,
Chia Zhen Chua,
Wai Hoe Ng,
Cheng Zhi Khor,
Jun Lyn Low,
Ashwin Mathew,
Kok Choon Cheah,
Saieeshwaran Menon,
Vikneshwara Shanmugam,
May Zoe Soe and
Kunji Kannan Sivaraman Kannan
* (Excluding Mailing and Handling)
Background and Objective: Tracheobronchopathia osteochondroplastica (TBOCP) is a rare, benign condition characterised by the presence of multiple bony and cartilaginous nodules in the tracheal and bronchial submucosa. Its etiology remains unknown, and clinical presentations and management vary.
Methods: We conducted a scoping review to evaluate clinical and radiological characteristics, diagnostic investigations and prognostic outcomes of TBOCP in adults by exploring Pubmed and SCOPUS databases.
Results: From the search results of 675 studies, 98 were included in this scoping review. TBOCP has a myriad of presenting symptoms and clinical severity but is notably an asthma mimic, displaying an obstructive pattern on spirometry. Bronchoscopic tools were the most common interventional diagnostic or management tool.
Conclusion: While the etiology of TBOCP remains unknown, clinicians are alerted to its varied presentations and classical histopathological and gross morphological appearance.
Keywords: Tracheobronchopathia osteochondroplastica, tracheobronchopathia osteoplastica, tracheopathia osteoplastica, scoping review, literature review, review.
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