Abstract

Purpose: Skin is an important delivery channel for medications, providing both local and systemic effects. One kind of novel medication delivery technology that is administered topically to the skin is called a topical film forming system. The thorough analysis examines how film-forming sprays have revolutionized a variety of fields, including wound care and medicine. The goal is to present a thorough summary of the assessment criteria, composition, and most recent advancements in film-forming sprays intended for wound healing.

Methods: The evaluation parameters including film formation, morphology, flexibility, drying time, pH, viscosity, skin irritation, water washability, bioadhesive strength, and container-related evaluations are provided in a systematic manner for film-forming sprays. The review presents findings from a range of research publications that demonstrate various approaches and strategies used to evaluate the properties and effectiveness of film-forming spray formulations.

Results: Examples from current research are given to show the variety of uses for film-forming sprays in wound healing. Formulations containing human epidermal growth factor (hEGF) and water- soluble chitosan, propolis from stingless bees, and a complexed polymer film-forming spray for diabetic wound dressing are among the research offerings. In terms of stability, wound closure acceleration, and regulated distribution of therapeutic substances, these formulations show encouraging results.

Conclusion: The review concludes that film-forming sprays represent a promising avenue in advanced wound care, offering advantages such as enhanced flexibility, prolonged adherence, and controlled drug delivery.

Keywords: Film forming spray, topical formulations, wound healing process, fick's law, topical wound management, polymeric films.