Cardiovascular & Hematological Disorders-Drug Targets

Author(s): Alberto Lazaro, Gloria Alvarez-Llamas, Julio Gallego-Delgado, Fernando de la Cuesta, Julio Osende, Ma Eugenia G. Barderas and Fernando Vivanco

DOI: 10.2174/187152909788488672

Pharmacoproteomics in Cardiac Hypertrophy and Atherosclerosis

Page: [141 - 148] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

Proteomics applications to study the molecular effects of drug administration (pharmacoproteomics) on left ventricular hypertrophy (LVH) and atherosclerosis are here reviewed. In most cases, an absence of complete normalization after treatment is revealed, in contrast to what is reported by classical approaches.

Keywords: Atherosclerosis, cardiac hypertrophy, proteomics, pharmacoproteomics